Catch me if you can – new stopped-flow NMR methods

Ran Wei – @RanWei_NMR

How fast can we go for real time in-situ reaction monitoring using solution NMR? Blink your eye, and the reaction is over. Check out our new stopped-flow NMR method for a race against the clock. A poster for #GlobalnmrTC2022 @LloydJonesLab @EdinburghChem pic.twitter.com/Wft4uQ0JpC

— Ran Wei (@RanWei_NMR) August 3, 2022

A new stopped-flow NMR apparatus was constructed to capture the fleeting information from irreversible chemical reactions at the millisecond timescale. With the aid of this technique, we are able to study short-lived intermediates, and evolving reactions that occur beyond the measurement deadtime of traditional NMR experiments (t1/2 = 45 ms).