Characterization of Flufenamic Acid Spatial Structure in scCO2 Based on 2D NOESY Data

Valentina Sobornova – @VSobornova7121

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— Valentina Sobornova (@VSobornova7121) July 16, 2024

We analyzed the conformational equilibria of flufenamic acid in various media using 2D NOESY spectroscopy and quantum chemical calculations. Our results demonstrate that supercritical carbon dioxide (scCO2) is an effective medium for altering and controlling the conformational preferences of slightly soluble compounds.