“Dark” phosphate no longer dark?

Jiaqi Lu – @Jiaqi_Lu22

Phosphates harbor a surprising secret – hidden clusters eluding spectroscopic detection. We expose their intricate behavior and employ chemical exchange saturation transfer (CEST) to discover new spectroscopic features, providing evidence for clustering. #GlobalnmrTC2023 pic.twitter.com/i9ub2rwkX1

— Jiaqi Lu (@Jiaqi_Lu22) July 19, 2023

Our research has unveiled the existence of hidden phosphate clusters, eluding spectroscopic detection. By manipulating solution conditions, notably pH, we expose their intricate behavior. Employing the power of chemical exchange saturation transfer, we discover new spectroscopic features, and provide further evidence for clustering. These results are important for studying phosphate function in the physiological environment.