Shadan Geshani – @ShGeshani
Vancomycin is a clinically-used glycopeptide antibiotic, used for the treatment of severe infections. Vancomycin kills bacteria by targeting cell wall precursors in the bacterial membrane, however, resistance mechanisms against this antibiotic have been widely known in pathogenic species. Molecular details of vancomycin’s action could only be studied in the absence of membranes. A better understanding of the molecular mechanism of vancomycin by ssNMR at atomic level will help to overcome this problem.
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