Hyperpolarization
Switching of the partially negative line effect of orthohydrogen via solvent types and their binary mixtures
Tomasz Ratajczyk - @TRatajczykonX
Under specific conditions, orthohydrogen generated from parahydrogen can appear to have a partially negative 1H-NMR line (PNL). We present that in some solvents, PNL appears with a positive-negative pattern, while in others, PNL has a negative-positive pattern. The modulation of PNL in a mixture of various solvents will be discussed.
Dynamic Nuclear Polarization using Nitrogen-Vacancy Center in Diamond
Shubham Kumar Debadatta - @shubham_k_deb
The study explores enhancing NMR sensitivity using dynamic nuclear polarization with diamond NV-center, aiming to transfer polarization to nearby nuclear spin using NV-electron spin and microwave pulses, avoiding traditional cryogenic methods and costly equipment.
Hunting for 15N DNP in liquids at 14 T
Natalie Ibbetson - @Natalieeibby
15N-DNP has been proven to work up to only 5 T, while other nuclei (13C, 31P) show enhancements up to 14.1 T. Here we show preliminary experiments conducted at 14.1 T on a solution of 15N-aniline doped with BDPA radical and numerical simulation of electron-nuclear hyperfine coupling.
Next-Generation Radical Designs for Direct Polarization Transfer in High-Field DNP
Ribal Jabbour - @JabbourRibal
Traditional DNP transfer employs an indirect, spin-diffusion mediated process, transferring polarization from nuclei on the PA to solvent nuclei, and then to the target molecule nuclei. In contrast, direct transfer involves immediate polarization from the PA to the target molecule, bypassing any intermediary nuclei. We show the distinctions between indirect and direct transfer methods using AMUPol, a widely-used bis-nitroxide, at magnetic fields ranging from 9 T to 14 T. We demonstrate that with ASYMPol-POK (larger e-e couplings), superior direct transfer performance in deuterated DNP solvent is shown compared to AMUPol.
Understanding Spin Dynamics and Polarization Transfer in Photoexcited Triplet Electron Spins
Sajith V Sadasivan - @v_sadasivan
Optically activated DNP techniques involving triplet state excitation use non-equilibrium electron spin polarization for room temperature measurements. Despite the advancements in the field, electron spin dynamics during polarization transfer to nuclei remain unexplored. This study aims to understand the electron spin dynamics of a photoexcited triplet system coupled to nuclei.
Using Electron Spin Clusters for Dynamic Nuclear Polarization
Raj Chaklashiya - @RajChaklashiya
Here we present design principles for Dynamic Nuclear Polarization (DNP) utilizing narrow-line Electron Spin Clusters (ESC) to achieve nuclear spin resonance matching (ESC-DNP) for 1H NMR signal enhancement at 7 T, with potential for wide radical design scope at high magnetic field and low microwave power.
Benchtop DNP Hyperpolarization with functional porous polarizing polymers
Julien Dieterich - @J_Dieterich_
Hyperpolarizing polymers (HYPOPs) are porous epoxy-amine polymers with covalently grafted nitroxide radicals. Their use in our HypFlow project aims to enable repeating multiple cycles of freeze-DNP-melt and liquid state analysis of a pure and undiluted sample. This work presents the first results of HYPOPs recorded in our 1 Tesla benchtop DNP polarizer operating at 77 Kelvin.
Magic NOVEL: Suppressing Electron-Electron Coupling Effects in Pulsed DNP
Amaria Javed
Dynamic nuclear polarization (DNP) boosts NMR sensitivity but suffers from electron-electron (e-e) interactions, reducing polarization transfer efficiency. We propose the Magic-NOVEL sequence to counteract these effects. Evaluating Lee-Goldburg NOVEL sequences, our theoretical and simulation results show enhanced electron-to-nucleus polarization transfer by weakening e-e interactions, improving DNP efficiency.
A short tour of the MAS-DNP lab at the NHMFL (Maglab)
Faith Scott - @faithscottdnp
I will showcase some of the improvements we have made to the MAS-DNP user program instrumentation over the last few years. This includes upgrades to the cooling cabinet and the 3.2 mm custom MAS-DNP probe.
Efficient Nuclear Polarization Using P1 Diamonds Under Magic Angle Spinning at 14.1 T from 30K to RT
Celeste Tobar - @Celestial_023
P1 center diamonds provide robust polarization for RT DNP, featuring unique spin properties and extended coherence and relaxation times. Our MAS-DNP experiments at 14.1 T (298K to 30K) reveal their efficiency and novel characteristics, showcasing their potential for NMR imaging and bio-NMR studies.
Exploring Adiabatic Inversion for Integrated Solid Effect
Mayur Manoj Jhamnani - @mayur_jhamnani
We explore the use of adiabatic inversion techniques to enhance the integrated solid effect (ISE). By carefully controlling the system parameters, we demonstrate how adiabatic inversion can be leveraged to improve the efficiency of polarization transfer via ISE. The findings have important implications for the development of triplet-DNP.