Videos
Single Chip Dynamic Nuclear Polarization Microsystems
During the 78th session of the Global NMR Discussion Meetings held on January 16st, 2024 via Zoom, Dr. Nergiz Sahin Solmaz from EPFL in Lausanne, Switzerland, gave a talk on the topic "Single Chip Dynamic Nuclear Polarization Microsystems". The recording serves as a tutorial.
Abstract:
Dynamic nuclear polarization (DNP) is one of the most powerful and versatile hyperpolarization methods to enhance nuclear magnetic resonance (NMR) signals. A major drawback of DNP is the cost and complexity of the required microwave hardware, especially at high magnetic fields and low temperatures. To overcome this drawback and with the focus on the study of nanoliter and subnanoliter samples, I will present single chip DNP microsystems where the microwave excitation and detection are performed locally on chip without the need of external microwave generators and transmission lines.
Dr. Nergiz Sahin Solmaz's website: https://people.epfl.ch/nergiz.sahin?lang=en
Inside an NMR Spectrometer
During the 73rd session of the Global NMR Discussion Meetings held on October 24th, 2023 via Zoom, Prof. Kazuyuki Takeda from Kyoto University in Japan, gave a talk on the topic "Inside an NMR Spectrometer". The recording serves as a tutorial.
Abstract: Let us take a brief look at what is happening inside an NMR spectrometer when we operate it, running pulse sequences and acquiring NMR signals. In particular, I will focus on open-resource, home-built NMR spectrometers we routinely use in our lab, and show how we apply them in the conventional and unconventional NMR experiments.
Website: http://kuchem.kyoto-u.ac.jp/bun/indiv/takezo/index_en.html http://www.kuchem.kyoto-u.ac.jp/organization/member/bk_200710/takezo_e.html
Microfluidics & Magnetic Resonance: A multidisciplinary challenge
During the 60th session of the Global NMR Discussion Meetings held on January 24th, 2023 via Zoom, Prof. Marcel Utz gave a talk on the topic "Microfluidics & Magnetic Resonance: A multidisciplinary challenge". The recording serves as a tutorial.
Abstract:
Microfluidic technology has rapidly advanced over the last two decades, and is increasingly transforming the practice of life science research, as well as (arguably more slowly) medical diagnostics. In particular, microfluidic assays are ideal platforms for the culture of cells, cell aggregates, and tissue slices, and form the basis of increasingly predictive disease models. Nuclear magnetic resonance, due to its non-invasive nature and ability to provide rich and detailed information on biological systems, is ideally suited to follow life processes in such microfluidic culture devices. However, the integration of high-performance NMR spectroscopy with microfluidic lab-on-a-chip devices is technically challenging due to the small sample volumes involved. Recent advances in hyperpolarization and alternative detection approaches offer important opportunities in this field. In this talk, I will give an overview of the opportunities and challenges in microfluidic NMR, and present some recent examples.
Prof. Marcel Utz is Professor of Magnetic Resonance, Microfluidics, and Complex Materials within Chemistry at the University of Southampton.
Website: https://utzgroup.ddns.net
Google scholar: https://scholar.google.com/citations?...
Dual NMR-EPR Detection in an Ultra Low Temperature DNP Spectrometer
During the 37th session of the Global NMR Discussion Meetings on Zoom, Kan Tagami, University of California, Santa Barbara (UCSB), gave a talk on the instrumentation aspects of a dynamic nuclear polarization spectrometer with dual nuclear magnetic resonance (NMR) and electron paramagnetic resonance (EPR) detection at ultra-low temperatures.
Speaker's biography:
2012 - 2016: B.S., Chemistry, College of William and Mary, USA.
2016 - present: Graduate Student Researcher, Chemistry, University of California - Santa Barbara, USA (Advisor: Prof. Songi Han)
Kan's research interest is in the spin physics and instrumentation of dynamic nuclear polarization (DNP) in solid state NMR. His goal is to improve the efficiency of solid state DNP under MAS through development of both EPR and NMR instruments, as well as use a wide variety of existing magnetic resonance techniques to characterize and exploit the underlying mechanisms of DNP. Currently, his focus is on development of a low temperature (30K), high field (7T) pulsed EPR/DNP spectrometer with magic angle spinning capabilities.
For more information, see the Han Lab website: https://han.chem.ucsb.edu
NMR Hardware
In Session 34 of the Global NMR Discussion Meetings, Dr. Mark Conradi gave a talk on NMR hardware.
Abstract: Many NMR spectroscopists are uncomfortable with hardware issues. This discussion will cover debugging techniques, so that malfunctions can be narrowed to particular components of the spectrometer. The testing of probes will be covered, as well as the basics of building special purpose probes. While you may not want to build your own 1.3 mm MAS probe, a probe for high-T, high-P, or in situ examination of batteries may be of interest.
Download Dr. Conradi's slides here: https://docs.google.com/presentation/... S
peaker's biography: Prof. Mark Conradi received his PhD in Physics under R.E. Norberg at Washington University in Saint Louis MO. He did a postdoctoral stint at Oak Ridge where he learned about free radicals and ESR. An assistant/ associate professorship followed at College of William and Mary in Virginia. He was a professor at Washington University for 29 years, moving five years ago to ABQMR, a small NMR contract research firm in New Mexico. Conradi's research themes included motions in molecular solids and metal-hydrogen systems and later the imaging of human lungs with hyperpolarized helium-3. Throughout, he has been interested in NMR hardware issues and techniques, such as NMR in diamond-anvil high-pressure cells and NMR in coin-cell batteries.
Google scholar: https://scholar.google.com/citations?...