Dissolution DNP-enhanced Zero- to Ultralow-Field NMR

In session 29 held on 8th June 2021, Román Picazo-Frutos gave a talk on dissolution dynamic nuclear polarization (DNP)-enhanced zero- to ultralow-Field nuclear magnetic resonance (NMR) spectroscopy, via Zoom. The video was recorded live during the presentation and serves as an educative lecture.

Bio:

2016: Bachelor's in Physics, Universitat de Valencia, Spain

2018: Master's degree in Physics, Johannes Gutenberg Universität, Germany

2019-present: PhD student, Helmholtz-Institut, Mainz, Germany (Prof. Dmitry Budker)

Román works on Zero- and Ultra-low field Nuclear Magnetic Resonance (ZULF NMR). Román is also interested in hyperpolarization, atomic physics, photonics and relaxometry in NMR.

Google scholar: https://scholar.google.com/citations?...

Budker group website: https://budker.uni-mainz.de/

ZULF blog post: getting rid of noise source in ZULF NMR : https://blog.zulf.eu/BP3.php

Abstract:

Zero- and ultra-low field NMR (ZULF-NMR) is a modality of NMR experiment that do not require strong magnets with applications ranging from molecular spectroscopy and chemical-reaction monitoring to dark-matter searches and exotic physics. However, it suffers from low sensitivity. In this work we combine dissolution Dynamic Nuclear Polarization (dDNP) to enhance biomolecules signals in a ZULF-NMR experiment. We discuss the scope of this hyperpolarization technique for ZULF NMR, such as the sample transfer and paramagnetic relaxation caused by the polarizing agent in DNP. We believe this technique can become an established choice for hyperpolarization in ZULF NMR.

Additional references:

Proton to carbon polarization transfer in NMR: https://onlinelibrary.wiley.com/doi/a...

Observing through metal containers at zero field: https://pubs.rsc.org/en/content/artic...

General Review on ZULF NMR: https://onlinelibrary.wiley.com/doi/a...

Link: https://youtu.be/XSp9Mr3ZHeU

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Brief Principles of Symmetry-Based Recoupling in Solid-State NMR