Ultrafast Laplace NMR and its applications
During the 95th session of the Global NMR Discussion Meetings held on January 14th, 2025, via Zoom, Prof. Ville-Veikko Telkki from the University of Oulu, Finland, gave a talk on the topic "Ultrafast Laplace NMR and its multidisciplinary applications". The recording serves as a tutorial.
Abstract: Laplace NMR (LNMR), comprising relaxation and diffusion experiments, provides unique information about molecular dynamics, structures and chemical environments. Multidimensional experiments enable correlating relaxation and diffusion parameters to probe different motional types and regimes as well as observing molecular exchange through relaxation or diffusion contrast. This presentation describes how multidimensional T1, T2 and T1r relaxation as well as diffusion experiments can be accelerated by orders of magnitude by spatial encoding and other means, allowing monitoring fast molecular processes in real time. These single-scan ultrafast LNMR experiments facilitate also significantly the use of nuclear spin hyperpolarization to boost sensitivity, making low concentration substances observable. The experiments are feasible also with low-field, single-sided magnets with inhomogeneous field, enhancing the portability and cost-efficiency of advanced NMR analysis. The representation highlights the multidisciplinary applications of the ultrafast LNMR methods, ranging from CO2-capturing cements, battery materials and dairy products to cellular metabolism, protein-ligand interactions, and atmospheric surfactant solutions.
Find out more about Prof. Tatyana Polenova's research: https://www.oulu.fi/en/researchers/ville-veikko-telkki